CENTONZE GIOVANNI

Autore e/o co-Autore di Pubblicazioni su Riviste Scientifiche Nazionali ed Internazionali

1. Centonze G. Picciotto G, Moretti M, Allocco E, Papurello M, Di Pietrantonj C, Marinaro L, Maimone P. La consulenza dietetico nutrizionale nel Dipartimento di Prevenzione per la promozione di stili alimentari salutari. Boll. Epidemiol. e Prospett. di Sanità Pubblica 59–75 (2024)
2. Sabella G, Centonze G, Lagano V, Scardino A, Belli F, Garzone G, Pardo C, Galbiati D, Pusceddu S, Mangogna A, Angerilli V, Fassan M, Vingiani A, Agnelli L, Pruneri G, Gobba S, Uccella S, La Rosa S, Sessa F, Capella C, Milione M. Unveiling the Prognostic Role of Synaptophysin in Conventional Colorectal Carcinomas. Neuroendocrinology. 2025 May 5:1-28. doi: 10.1159/000545979. Epub ahead of print. PMID: 40324347.
3. Sabella G, Centonze G, Maisonneuve P, Grillo F, Lagano V, Garzone G, Pardo C, Filugelli M, Mietta A, Simbolo M, Fabbri A, Mangogna A, Prinzi N, Pusceddu S, Rolli L, Bercich L, Grisanti S, Benvenuti MR, Pastorino U, Roz L, Scarpa A, Berruti A, Capella C, Milione M. Oncocytic and spindle cell typical carcinoids of lung: different immunophenotype and biological behavior. J Pathol Clin Res. 2025 Mar;11(2):e70020. doi: 10.1002/2056-4538.70020. PMID: 40047117; PMCID: PMC11883411.
4.  Angerilli V, Sabella G, Simbolo M, Lagano V, Centonze G, Gentili M, Mangogna A, Coppa J, Munari G, Businello G, Borga C, Schiavi F, Pusceddu S, Leporati R, Oldani S, Fassan M, Milione M. Comprehensive genomic and transcriptomic characterization of high-grade gastro-entero-pancreatic neoplasms. Br J Cancer. 2024 May 10. doi: 10.1038/s41416-024-02705-8. Epub ahead of print. PMID: 38729995.
5.  Parodi M, Centonze G, Murianni F, Orecchia P, Andriani F, Roato I, Gardelli C, Balsamo M, Moro M, Taiè G, Pastorino U, Petretto A, Lavarello C, Milione M, Sozzi G, Roz L, Vitale M, Bertolini G. Hybrid epithelial-mesenchymal status of lung cancer dictates metastatic success through differential interaction with NK cells. J Immunother Cancer. 2024 Mar 7;12(3):e007895. doi: 10.1136/jitc-2023-007895. PMID: 38458638; PMCID: PMC10921513.
6. Simbolo M, Centonze G, Gkountakos A, Monti V, Maisonneuve P, Golovco S, Sabella G, Del Gobbo A, Gobbo S, Ferrero S, Fabbri A, Pardo C, Garzone G, Prinzi N, Pusceddu S, Testi A, Rolli L, Mangogna A, Bercich L, Benvenuti MR, Bria E, Pilotto S, Berruti A, Pastorino U, Capella C, Infante M, Milella M, Scarpa A, Milione M. Characterization of two transcriptomic subtypes of marker-null large cell carcinoma of the lung suggests different origin and potential new therapeutic perspectives. Virchows Arch. 2024 May;484(5):777-788. doi: 10.1007/s00428-023-03721-4. Epub 2024 Jan 3. PMID: 38168015; PMCID:.
7. Graziano P, Parente P, Centra F, Milione M, Centonze G, Volante M, Cavazza A, Urbano D, Di Maggio G, Balsamo T, Di Micco C, Rossi G, Rossi A, Muscarella LA. Clinical impact of mixed pulmonary carcinoma and carcinoid: the driver from their mono-clonal origin. Virchows Arch. 2024 Jan;484(1):37-46. doi: 10.1007/s00428-023-03663-x. Epub 2023 Sep 29. PMID: 37773451.
8. Rota S, Quattrone P, Centonze G, Dagrada G, Ottini A, Colombo E, Nuzzolese I, Calareso G, Franceschini M, Iacovelli NA, Perrone F, Tamborini E, Cavalieri S. NUT carcinoma of the submandibular gland: A case report. Cancer Rep (Hoboken). 2023 Dec;6(12):e1900. doi: 10.1002/cnr2.1900. Epub 2023 Sep 8. PMID: 37680121; PMCID: PMC10728538.
9. Mattiolo P, Gkountakos A, Centonze G, Bevere M, Piccoli P, Ammendola S, Pedrazzani C, Landoni L, Cingarlini S, Milella M, Milione M, Luchini C, Scarpa A, Simbolo M. Transcriptome analysis of primary sporadic neuroendocrine tumours of the intestine identified three different molecular subgroups. Pathol Res Pract. 2023 Aug;248:154674. doi: 10.1016/j.prp.2023.154674. Epub 2023 Jul 7. PMID: 37454491.
10. Cattaneo L, Centonze G, Sabella G, Lagano V, Angerilli V, Pardo C, Bertani E, Spada F, Prinzi N, Pusceddu S, Fassan M, Fazio N, Milione M. Digestive MiNENs: Could histological classification and molecular characterization drive clinical outcome and therapeutic approach? Crit Rev Oncol Hematol. 2023 Aug;188:104044. doi: 10.1016/j.critrevonc.2023.104044. Epub 2023 Jun 1. PMID: 37268174.
11.  Kirienko M, Centonze G, Sabella G, Sollai M, Sollini M, Lan X, Chen H, Terracciano L, Seregni E, Milione M. FAP expression in alpha cells of Langherhans insulae-implications for FAPI radiopharmaceuticals’ use. Eur J Nucl Med Mol Imaging. 2023 Aug;50(10):3042-3049. doi: 10.1007/s00259-023-06246-9. Epub 2023 May 4. PMID: 37140668
12.  Lauricella E, Manicone A, Cavallo F, Dagrada GP, Centonze G, Bertulli R, Quattrone P, Porta C, Cives M. Adamantinoma-like Ewing sarcoma of the salivary glands: a case report and systematic literature review. Ther Adv Med Oncol. 2023 Apr 17;15:17588359231165979. doi: 10.1177/17588359231165979. PMID: 37113735;
13. Centonze G, Maisonneuve P, Simbolo M, Lagano V, Grillo F, Prinzi N, Pusceddu S, Missiato L, Colantuono M, Sabella G, Bercich L, Mangogna A, Rolli L, Grisanti S, Benvenuti MR, Pastorino U, Roz L, Scarpa A, Berruti A, Capella C, Milione M. Ascl1 and OTP tumour expressions are associated with disease-free survival in lung atypical carcinoids. Histopathology. 2023 May;82(6):870-884. doi: 10.1111/his.14873. Epub 2023 Feb 21. PMID: 36720841.
14.  Centonze G, Maisonneuve P, Simbolo M, Lagano V, Grillo F, Fabbri A, Prinzi N, Garzone G, Filugelli M, Pardo C, Mietta A, Pusceddu S, Sabella G, Bercich L, Mangogna A, Rolli L, Grisanti S, Benvenuti MR, Pastorino U, Roz L, Scarpa A, Berruti A, Capella C, Milione M. Lung Carcinoid Tumors: Histology and Ki-67, The Eternal Rivalry. Histopathology. 2022 Oct 14. doi: 10.1111/his.14819. Epub ahead of print. PMID: 36239545.
15.  Centonze G, Maisonneuve P, Prinzi N, Pusceddu S, Albarello L, Pisa E, Barberis M, Vanoli A, Spaggiari P, Bossi P, Cattaneo L, Sabella G, Solcia E, La Rosa S, Grillo F, Tagliabue G, Scarpa A, Papotti M, Volante M, Mangogna A, Del Gobbo A, Ferrero S, Rolli L, Roca E, Bercich L, Benvenuti M, Messerini L, Inzani F, Pruneri G, Busico A, Perrone F, Tamborini E, Pellegrinelli A, Kankava K, Berruti A, Pastorino U, Fazio N, Sessa F, Capella C, Rindi G, Milione M. Prognostic Factors Across Poorly Differentiated Neuroendocrine Neoplasms: a Pooled Analysis. Neuroendocrinology. 2022 Nov 23. doi: 10.1159/000528186. Epub ahead of print. PMID: 36417840.
16.  Simbolo M, Centonze G, Giudice L, Grillo F, Maisonneuve P, Gkountakos A, Ciaparrone C, Cattaneo L, Sabella G, Giugno R, Bossi P, Spaggiari P, Del Gobbo A, Ferrero S, Mastracci L, Fabbri A, Filugelli M, Garzone G, Prinzi N, Pusceddu S, Testi A, Monti V, Rolli L, Mangogna A, Bercich L, Benvenuti MR, Bria E, Pilotto S, Berruti A, Pastorino U, Capella C, Infante M, Milella M, Scarpa A, Milione M. Combined Large Cell Neuroendocrine Carcinomas of the Lung: Integrative Molecular Analysis Identifies Subtypes with Potential Therapeutic Implications. Cancers (Basel). 2022 Sep 24;14(19):4653. doi: 10.3390/cancers14194653. PMID: 36230576; PMCID: PMC9562868.
17.  Sorrentino L, Sileo A, Daveri E, Battaglia L, Guaglio M, Centonze G, Sabella G, Patti F, Villa S, Milione M, Belli F, Cosimelli M. Impact of Microscopically Positive (≤1 mm) Distal Margins on Disease Recurrence in Rectal Cancer Treated by Neoadjuvant Chemoradiotherapy. Cancers (Basel). 2023 Mar 17;15(6):1828. doi: 10.3390/cancers15061828. PMID: 36980714; PMCID: PMC10047023.
18. Gasparini P, Casanova M, Centonze G, Borzi C, Bergamaschi L, Collini P, Testi A, Chiaravalli S, Massimino M, Sozzi G, Ferrari A, Moro M. Establishment of 6 pediatric rhabdomyosarcoma patient’s derived xenograft models closely recapitulating patients’ tumor characteristics. Tumori. 2022 Sep 16:3008916221110266. doi: 10.1177/03008916221110266. Epub ahead of print. PMID: 36114629.
19. Doldi V, Lecchi M, Ljevar S, Colecchia M, Campi E, Centonze G, Marenghi C, Rancati T, Miceli R, Verderio P, Valdagni R, Gandellini P, Zaffaroni N. Potential of the Stromal Matricellular Protein Periostin as a Biomarker to Improve Risk Assessment in Prostate Cancer. Int J Mol Sci. 2022 Jul 20;23(14):7987. doi: 10.3390/ijms23147987. PMID: 35887333.
20.  Simbolo M, Centonze G, Ali G, Garzone G, Taormina S, Sabella G, Ciaparrone C, Mafficini A, Grillo F, Mangogna A, Volante M, Mastracci L, Fontanini G, Pilotto S, Bria E, Infante M, Capella C, Rolli L, Pastorino U, Milella M, Milione M, Scarpa A. Integrative molecular analysis of combined small-cell lung carcinomas identifies major subtypes with different therapeutic opportunities. ESMO Open. 2022 Feb;7(1):100308. doi: 10.1016/j.esmoop.2021.100308. Epub 2021 Dec 21. PMID: 34952268; PMCID: PMC8695295.
21. Moro M, Fortunato O, Bertolini G, Mensah M, Borzi C, Centonze G, Andriani F, Di Paolo D, Perri P, Ponzoni M, Pastorino U, Sozzi G, Boeri M. MiR-486-5p Targets CD133+ Lung Cancer Stem Cells through the p85/AKT Pathway. Pharmaceuticals (Basel). 2022 Feb 28;15(3):297. doi: 10.3390/ph15030297. PMID: 35337095; PMCID: PMC8951736.
22. Romanzi A, Centonze G, Sabella G, Cattaneo L, Battiston C, Lorenzo ND, Milanesi M, Putortì A, Rossi F, Scolaro R, Zanardo M, Vignati B, Vannelli A. Colorectal medullary carcinoma: heterogeneous presentations of a rare clinico-pathological entity. Report of two cases. Tumori. 2022 Mar 20:3008916221082996. doi: 10.1177/03008916221082996. Epub ahead of print. PMID: 35311395.
23.  Angerilli V, Sabella G, Centonze G, Lonardi S, Bergamo F, Mangogna A, Pietrantonio F, Fassan M, Milione M. BRAF-mutated colorectal adenocarcinomas: Pathological heterogeneity and clinical implications. Crit Rev Oncol Hematol. 2022 Apr;172:103647. doi: 10.1016/j.critrevonc.2022.103647. Epub 2022 Mar 4. PMID: 35248712.
24.  Gkountakos A, Centonze G, Vita E, Belluomini L, Milella M, Bria E, Milione M, Scarpa A, Simbolo M. Identification of Targetable Liabilities in the Dynamic Metabolic Profile of EGFR- Mutant Lung Adenocarcinoma: Thinking beyond Genomics for Overcoming EGFR TKI Resistance. Biomedicines. 2022 Jan 26;10(2):277. doi: 10.3390/biomedicines10020277. PMID: 35203491; PMCID: PMC8869286.
25. Massironi S, Facciotti F, Cavalcoli F, Amoroso C, Rausa E, Centonze G, Cribiù FM, Invernizzi P, Milione M. Intratumor Microbiome in Neuroendocrine Neoplasms: A New Partner of Tumor Microenvironment? A Pilot Study. Cells. 2022 Feb 16;11(4):692. doi: 10.3390/cells11040692. PMID: 35203339; PMCID: PMC8870382.
26. Prisciandaro M, Antista M, Raimondi A, Corti F, Morano F, Centonze G, Sabella G, Mangogna A, Randon G, Pagani F, Prinzi N, Niger M, Corallo S, Castiglioni di Caronno E, Massafra M, Bartolomeo MD, de Braud F, Milione M, Pusceddu S. Biomarker Landscape in Neuroendocrine Tumors With High-Grade Features: Current Knowledge and Future Perspective. Front Oncol. 2022 Feb 4;12:780716. doi: 10.3389/fonc.2022.780716. PMID: 35186729; PMCID: PMC8856722.
27. Simbolo M, Bersani S, Vicentini C, Taormina SV, Ciaparrone C, Bagante F, Rusev B, Centonze G, Montresor M, Brunelli M, Pedron S, Mafficini A, Paolino G, Mattiolo P, Conci S, Milione M, Guglielmi A, Ruzzenente A, Scarpa A, Luchini C. Molecular characterization of extrahepatic cholangiocarcinoma: perihilar and distal tumors display divergent genomic and transcriptomic profiles. Expert Opin Ther Targets. 2021 Dec;25(12):1095-1105. doi: 10.1080/14728222.2021.2013801. Epub 2021 Dec 22. PMID: 34873971.
28.  Borzi C, Caiola E, Ganzinelli M, Centonze G, Boeri M, Milione M, Broggini M, Sozzi G, Moro M. miR-17 Epigenetic Modulation of LKB1 Expression in Tumor Cells Uncovers a New Group of Patients With Poor-Prognosis NSCLC. J Thorac Oncol. 2021 Sep;16(9):e68-e70. doi: 10.1016/j.jtho.2021.06.032. PMID: 34426000.
29. Pontis F, Roz L, Mensah M, Segale M, Moro M, Bertolini G, Petraroia I, Centonze G, Ferretti AM, Suatoni P, Pastorino U, Fortunato O, Sozzi G. Circulating extracellular vesicles from individuals at high-risk of lung cancer induce pro-tumorigenic conversion of stromal cells through transfer of miR-126 and miR-320. J Exp Clin Cancer Res. 2021 Jul 21;40(1):237. doi: 10.1186/s13046-021- 02040-3. PMID: 34289890; PMCID: PMC8293562.
30.  Kankava K, Maisonneuve P, Mangogna A, Centonze G, Cattaneo L, Prinzi N, Pusceddu S, Fazio N, Pisa E, Di Domenico S, Bertani E, Mazzaferro V, Albertelli M, Grillo F, Milione M. Prognostic features of gastro-entero-pancreatic neuroendocrine neoplasms in primary and metastatic sites: Grade, mesenteric tumour deposits and emerging novelties. J Neuroendocrinol. 2021 Aug;33(8):e13000. doi: 10.1111/jne.13000. Epub 2021 Jul 16. PMID: 34268808.
31. Belfiore A, Centonze G, Maisonneuve P, Riva C, Morelli D, Mangogna A, Sabella G, Pruneri G, Milione M. COVID-19 Pandemic: Huge Stress Test for Health System Could Be a Great Opportunity to Update the Workflow in a Modern Surgical Pathology. Cancers (Basel). 2021 Jun 30;13(13):3283. doi: 10.3390/cancers13133283. PMID: 34209009; PMCID: PMC8268969.
32. Di Paolo D, Pontis F, Moro M, Centonze G, Bertolini G, Milione M, Mensah M, Segale M, Petraroia I, Borzi C, Suatoni P, Brignole C, Perri P, Ponzoni M, Pastorino U, Sozzi G, Fortunato O. Cotargeting of miR-126-3p and miR-221-3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling. Mol Oncol. 2021 Jun 9. doi: 10.1002/1878-0261.13036. Epub ahead of print. PMID: 34107168.
33. Grossi U, Bonis A, Carrington EV, Mazzobel E, Santoro GA, Cattaneo L, Centonze G, Gallo G, Kazemi Nava A, Romano M, Di Tanna GL, Zanus G. Mixed adenoneuroendocrine carcinoma (MANEC) of the lower gastrointestinal tract: A systematic review with Bayesian hierarchical survival analysis. Eur J Surg Oncol. 2021 May 14:S0748-7983(21)00497-2. doi: 10.1016/j.ejso.2021.05.021. Epub ahead of print. PMID: 34052038.
34. Bertolini G, Cancila V, Milione M, Lo Russo G, Fortunato O, Zaffaroni N, Tortoreto M, Centonze G, Chiodoni C, Facchinetti F, Pollaci G, Taiè G, Giovinazzo F, Moro M, Camisaschi C, De Toma A, D’Alterio C, Pastorino U, Tripodo C, Scala S, Sozzi G, Roz L. A novel CXCR4 antagonist counteracts paradoxical generation of cisplatin-induced pro-metastatic niches in lung cancer. Mol Ther. 2021 Oct 6;29(10):2963-2978. doi: 10.1016/j.ymthe.2021.05.014. Epub 2021 May 21. PMID: 34023505.
35. Centonze G, Lagano V, Sabella G, Mangogna A, Garzone G, Filugelli M, Belmonte B, Cattaneo L, Crisafulli V, Pellegrinelli A, Simbolo M, Scarpa A, Spaggiari P, Brambilla T, Pusceddu S, Prinzi N, Anichini A, Tripodo C, Milione M. Myeloid and T-Cell Microenvironment Immune Features Identify Two Prognostic Sub-Groups in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms. J Clin Med. 2021 Apr 17;10(8):1741. doi: 10.3390/jcm10081741. PMID: 33920514; PMCID: PMC8072982.
36. Borzi C, Ganzinelli M, Caiola E, Colombo M, Centonze G, Boeri M, Signorelli D, Caleca L, Rulli E, Busico A, Capone I, Pastorino U, Marabese M, Milione M, Broggini M, Garassino MC, Sozzi G, Moro M. LKB1 Down-Modulation by miR-17 Identifies Patients With NSCLC Having Worse Prognosis Eligible for Energy-Stress-Based Treatments. J Thorac Oncol. 2021 Aug;16(8):1298- 1311. doi: 10.1016/j.jtho.2021.04.005. Epub 2021 Apr 19. PMID: 33887464.
37. Delconte G, Cavalcoli F, Magarotto A, Centonze G, Bezzio C, Cattaneo L, Rausa E, Kelly ME, Bonitta G, Milione M, Masci E. Does ProCore fine needle biopsy really improve the clinical outcome of endoscopic ultrasound-guided sampling of pancreatic masses? Dig Dis. 2021 Mar 29. doi: 10.1159/000516177.
38. Fassan M, Milione M, Maddalena G, Cremolini C, Schirripa M, Pietrantonio F, Pella N, Dell’Aquila E, Sperti E, Zichi C, Bergamo F, Volante M, Boccaccino A, Morano F, Cortiula F, De Maglio G, Rimassa L, Smiroldo V, Calvetti L, Aprile G, Salvatore L, Santini D, Salmaso R, Centonze G, Biason P, Borga C, Lonardi S, Zagonel V, Dei Tos AP, Di Maio M, Loupakis F. Synaptophysin expression in V600EBRAF-mutated advanced colorectal cancers identifies a new subgroup of tumours with worse prognosis. Eur J Cancer. 2021 Mar;146:145-154. doi: 10.1016/j.ejca.2021.01.016. Epub 2021 Feb 16.
39. Centonze G, Biganzoli D, Prinzi N, Pusceddu S, Mangogna A, Tamborini E, Perrone F, Busico A, Lagano V, Cattaneo L, Sozzi G, Roz L, Biganzoli E, Milione M. Beyond Traditional Morphological Characterization of Lung Neuroendocrine Neoplasms: In Silico Study of Next- Generation Sequencing Mutations Analysis across the Four World Health Organization Defined Groups. Cancers (Basel). 2020 Sep 24;12(10):E2753. doi: 10.3390/cancers12102753.
40. Milione M, Boeri M, Cantarutti A, Centonze G, Busico A, Suatoni P, Garzone G, Cattaneo L, Tamborini E, Perrone F, Mangogna A, Corrao G, Pruneri G, Sozzi G, Anichini A, Pastorino U. Improved Prognostic Prediction in Never-Smoker Lung Cancer Patients by Integration of a Systemic Inflammation Marker with Tumor Immune Contexture Analysis. Cancers (Basel). 2020 Jul 7;12(7):1828. doi: 10.3390/cancers12071828.
41. Moretto R, Corallo S, Belfiore A, Rossini D, Boccaccino A, Lonardi S, Centonze G, Morano F, Germani MM, Loupakis F, Morelli L, Urbani L, Brich S, Marmorino F, Prisciandaro M, Aprile G,Fassan M, Cillo U, Cattaneo L, Fontanini G, De Braud F, Falcone A, Milione M, Pietrantonio F, Cremolini C. Prognostic impact of immune-microenvironment in colorectal liver metastases resected after triplets plus a biologic agent: A pooled analysis of five prospective trials. Eur J Cancer. 2020 Aug;135:78-88. doi: 10.1016/j.ejca.2020.04.045. Epub 2020 Jun 15.
42. Pusceddu S, Corti F, Milione M, Centonze G, Prinzi N, Torchio M, de Braud F. Are Cyclin- Dependent Kinase 4/6 Inhibitors Without Future in Neuroendocrine Tumors? Oncologist. 2020 May 20;25(8):e1257-8. doi: 10.1634/theoncologist.2020-0298
43. Milione M, Maisonneuve P, Grillo F, Mangogna A, Centonze G, Prinzi N, Pusceddu S, Garzone G, Cattaneo L, Busico A, Bossi P, Spaggiari P, Pellegrinelli A, Del Gobbo A, Ferrero S, Kankava K, Pruneri G, Rolli L, Roca E, Bercich L, Tironi A, Benvenuti MR, Gallazzi MS, Romano R, Berruti A, Pastorino U, Capella C. Ki-67 Index of 55% Distinguishes Two Groups of Bronchopulmonary Pure and Composite Large Cell Neuroendocrine Carcinomas with Distinct Prognosis. Neuroendocrinology. 2020 May 4. doi: 10.1159/000508376.
44. Bianchi F, Alexiadis S, Camisaschi C, Truini M , Centonze G, Milione M, Balsari A, Tagliabue E, Sfondrini L . TLR3 Expression Induces Apoptosis in Human Non-Small-Cell Lung Cancer. Int J Mol Sci. 2020;21(4):E1440. Published 2020 Feb 20. doi:10.3390/ijms21041440
45. Centonze G, Mangogna A, Salviato T, Belmonte B, Cattaneo L, Monica M, Garzone G, Brambilla C, Pellegrinelli A, Melotti F, Testi A, Monti V, Kankava K, Gasparini P,   Dagrada G, Mazzaferro V, Cotsoglou C, Collini P, Pruneri G and   Milione M. Gastroblastoma in adulthood: a rarity among rare cancers. A case report and review of the literature. Case Reports in Pathology 2019. https://doi.org/10.1155/2019/4084196
46. Bianchi F, Milione M, Casalini P, Centonze G, Le Noci VM, Storti C, Alexiadis S, Truini M, Sozzi G, Pastorino U, Balsari A, Tagliabue E, Sfondrini L. Toll-like receptor 3 as a new marker to detect high risk early stage Non-Small-Cell Lung Cancer patients. Sci Rep. 2019 Oct 3;9(1):14288. doi: 10.1038/s41598-019-50756-2
47. Lasota J, Chłopek M, Lamoureux J, Christiansen J, Kowalik A, Wasąg B, Felisiak-Gołąbek A, Agaimy A, Biernat W, Canzonieri V, Centonze G, Chmielik E, Daum O, Dubová M, Dziuba I, Goertz S, Góźdź S, Guttmejer-Nasierowska A, Haglund C, Hałoń A, Hartmann A, Inaguma S, Iżycka-Świeszewska E, Kaczorowski M, Kita P, Kołos M, Kopczyński J, Michal M, Milione M, Okoń K, Pęksa R, Pyzlak M, Ristimäki A, Ryś J, Szostak B, Szpor J, Szumiło J, Teresiński L, Waloszczyk P, Wejman J, Wesołowski W, Miettinen M. Colonic Adenocarcinomas Harboring NTRK Fusion Genes: A Clinicopathologic and Molecular Genetic Study of 16 Cases and Review of the Literature. Am J Surg Pathol. 2019 Sep 23. doi: 10.1097/PAS.0000000000001377
48. Busico A, Maisonneuve P, Prinzi N, Pusceddu S, Centonze G, Garzone G, Pelligrinelli A, Giacomelli L, Mangogna A, Paolino C, Belfiore A, Kankava K, Perrone F, Tamborini E, Pruneri G, Fazio N, Milione M. Gastroenteropancreatic High-Grade Neuroendocrine Neoplasms (H-NENs): histology and molecular analysis, two sides of the same coin. Neuroendocrinology. 2019 Sep 27. doi: 10.1159/000503722.
49. Gasparini P, Fortunato O, De Cecco L, Casanova M, Iannó MF, Carenzo A, Centonze G, Milione M, Collini P, Boeri M, Dugo M, Gargiuli C, Mensah M, Segale M, Bergamaschi L, Chiaravalli S, Sensi ML, Massimino M, Sozzi G, Ferrari A. Age-Related Alterations in Immune Contexture Are Associated with Aggressiveness in Rhabdomyosarcoma. Cancers (Basel). 2019 Sep 17;11(9). pii: E1380. doi: 10.3390/cancers11091380.
50. Moro M, Di Paolo D, Milione M, Centonze G, Bornaghi V, Borzi C, Gandellini P, Perri P, Pastorino U, Ponzoni M, Sozzi G, Fortunato O. Coated cationic lipid-nanoparticles entrapping miR- 660 inhibit tumor growth in patient-derived xenografts lung cancer models. J Control Release. 2019 Aug 28;308:44-56. doi: 10.1016/j.jconrel.2019.07.006.
51. Milione M, Miceli R, Barretta F, Pellegrinelli A, Spaggiari P, Tagliabue G, Centonze G, Paolino C, Mangogna A, Kankava K, Pusceddu S, Giacomelli L, Corti A, Cotsoglou C, Mazzaferro V, Sozzi G, de Braud F, Pruneri G, Anichini A. Microenvironment and tumor inflammatory features improve prognostic prediction in gastro-entero-pancreatic neuroendocrine neoplasms. J Pathol Clin Res. 2019 May 28. doi: 10.1002/cjp2.135
52. Boeri M, Milione M, Proto C, Signorelli D, Lo Russo G, Galeone C, Verri C, Mensah M, Centonze G, Martinetti A, Sottotetti E, Pastorino U, Garassino MC, Sozzi G. Circulating miRNAs and PD-L1 Tumor Expression Are Associated with Survival in Advanced NSCLC Patients Treated with Immunotherapy: a Prospective Study. Clin Cancer Res. 2019 Apr 1;25(7):2166-2173. doi: 10.1158/1078-0432.CCR-18-1981
53. Vernieri C, Pusceddu S, Fucà G, Indelicato P, Centonze G, Castagnoli L, Ferrari E, Ajazi A, Pupa S, Casola S, Foiani M, Mazzaferro V, Pruneri G, Milione M, de Braud F. Impact of systemic and tumor lipid metabolism on everolimus efficacy in advanced pancreatic neuroendocrine tumors (pNETs). Int J Cancer. 2019 Apr 1;144(7):1704-1712. doi: 10.1002/ijc.32042
54. Fortunato O, Borzi C, Milione M, Centonze G, Conte D, Boeri M, Verri C, Moro M, Facchinetti F, Andriani F, Roz L, Caleca L, Huber V, Cova A, Camisaschi C, Castelli C, Cancila V, Tripodo C, Pastorino U, Sozzi G. Circulating mir-320a promotes immunosuppressive macrophages M2 phenotype associated with lung cancer risk. Int J Cancer. 2019 Jun 1;144(11):2746-2761. doi: 10.1002/ijc.31988.
55. Milione M, Maisonneuve P, Pellegrinelli A, Spaggiari P, Centonze G, Coppa J, Delconte G, Droz Dit Busset M, Lanhazo O, Pruneri G, Mazzaferro V. Ki-67 and presence of liver metastases identify different progression-risk classes in pancreatic neuroendocrine neoplasms (pNEN) undergoing resection. Eur J Surg Oncol. 2019 May;45(5):755-760. doi: 10.1016/j.ejso.2018.10.052
56. Lo Russo G, Moro M, Sommariva M, Cancila V, Boeri M, Centonze G, Ferro S, Ganzinelli M, Gasparini P, Huber V, Milione M, Porcu L, Proto C, Pruneri G, Signorelli D, Sangaletti S, Sfondrini L, Storti C, Tassi E, Bardelli A, Marsoni S17, Torri V, Tripodo C, Colombo MP, Anichini A, Rivoltini L, Balsari A, Sozzi G, Garassino M. Antibody-Fc/FcR Interaction on Macrophages as a Mechanism for Hyperprogressive Disease in Non-Small Cell Lung Cancer Subsequent to PD-1/PD- L1 Blockade. Clin Cancer Res. 2019 Feb 1;25(3):989-999. doi: 10.1158/1078-0432.CCR-18-1390.
57. Moro M, Caiola E, Ganzinelli M, Zulato E, Rulli E, Marabese M, Centonze G, Busico A, Pastorino U, de Braud FG, Vernieri C, Simbolo M, Bria E,Scarpa A, Indraccolo S, Broggini M, Sozzi G, Garassino MC. Metformin Enhances Cisplatin-Induced Apoptosis and Prevents Resistance to Cisplatin in Co-mutated KRAS/LKB1 NSCLC. J Thorac Oncol. 2018 Nov;13(11):1692-1704. doi: 10.1016/j.jtho.2018.07.102
58. Bertolini G, Bergamaschi L, Ferrari A, Renne SL, Collini P, Gardelli C, Barisella M, Centonze G, Chiaravalli S, Paolino C, Milione M,Massimino M, Casanova M, Gasparini P. PD-L1 assessment in pediatric rhabdomyosarcoma: a pilot study. BMC Cancer. 2018 Jun 13;18(1):652.
59. Milione M, Maisonneuve P, Pellegrinelli A, Grillo F, Albarello L, Spaggiari P, Vanoli A, Tagliabue G, Pisa E, Messerini L, Centonze G, Inzani F, Scarpa A, Papotti M, Volante M, Sessa F, Fazio N, Pruneri G, Rindi G, Solcia E, La Rosa S, Capella C. Ki67 proliferative index of the neuroendocrine component drives MANEC prognosis. Endocr Relat Cancer. 2018 May;25(5):583-593.
60. Borzi C, Calzolari L, Centonze G, Milione M, Sozzi G, Fortunato O. mir-660-p53-mir-486 Network: A New Key Regulatory Pathway in Lung Tumorigenesis. Int J Mol Sci. 2017 Jan 23;1.
61. Milione M, Maisonneuve P, Pellegrinelli A, Pusceddu S, Centonze G, Dominoni F, Brambilla C, Rubino M, Faggiano A, Buzzoni R, Concas L, Giacomelli L, Coppa J, Mazzaferro V, de Braud F. Loss of succinate dehydrogenase subunit B (SDHB) as a prognostic factor in advanced ileal well- differentiated neuroendocrine tumors. Endocrine. 2017 Sep;57(3):512-517. doi: 10.1007/s12020- 016-1180-6
62. Gasparini P, Casanova M, Villa R, Collini P, Alaggio R, Zin A, Bonvini P, Antonescu CR, Boldrini R, Caserini R, Moro M, Centonze G, Meazza C, Massimino M, Bergamaschi L, Luksch R, Chiaravalli S, Bisogno G, Zaffaroni N, Daidone M, Sozzi G, Ferrari A. Anaplastic lymphoma kinase aberrations correlate with metastatic features in pediatric rhabdomyosarcoma. Oncotarget. 2016 Sep 13;7(37):58903-58914. doi: 10.18632/oncotarget.10368.
63. Pelosi G, Fabbri A, Tamborini E, Perrone F, Testi AM, Settanni G, Busico A, Centonze G, Braidotti P, Bulfamante G, De Braud F, Garassino M, Pastorino U. Challenging Lung Carcinoma with Coexistent ΔNp63/p40 and Thyroid Transcription Factor-1 Labeling Within the Same Individual Tumor Cells. J Thorac Oncol. 2015 Oct;10(10):1500-2. doi: 10.1097/JTO.0000000000000553